 Recent advancements in drug delivery technologies utilizing misoperous silicon nanoparticles, MSNs, have resulted in a path-breaking revolution in the approach towards diagnosis and therapy. MSNs are ordered porous materials with high-thermal, chemical and mechanical properties that have garnered immense attention as drug carriers due to their distinctive features over other materials. They can be synthesized using a relatively simple process, making it cost-effective. By controlling the parameters during synthesis, the morphology, pore size and volume and particle size can be transformed accordingly. MSNs have been used for loading small molecules as well as macromolecules such as proteins, CERNA, and so forth, making them a versatile carrier. Researchers have explored the potential of MSNs in drug-resistant chemotherapy and antimicrobial therapy by modifying the framework of MSNs. However, there is a lack of thorough understanding of its interaction with a biological system which poses a major hurdle in the passage of this carrier to the clinical level. Several patents have been filed in the field of MSNs for therapeutic purposes. This article was authored by Rima Narayan, Usha Waianayak, Ashok M. Raichur, and others. We are article.tv, links in the description below.