 This systematic review and meta-analysis aims to determine the efficacy of interventions that incorporate apps in facilitating weight loss and health behavior change in the Asian population. The results show that supplementing multi-component usual care with an app led to greater weight loss, but more evidence is needed to determine the long-term efficacy of apps and address low uptake. Future research should focus on determining the efficacy of each component of the multi-component intervention to facilitate effective and cost-efficient weight management studies. This article was authored by Su Min-ong, Juliana Chen, Jiahuan Liu, and others.