 Just like we have adrenergic agonists, we also can have adrenergic antagonists. So they help to antagonize or dampen that adrenergic, that sympathetic response. And so we have to think about alpha versus beta adrenergic agonists. And sometimes they're also called alpha and beta blockers. So you might be more familiar with that. And so just think about what they do. Alpha adrenergic antagonists, they help to antagonize or counteract that alpha response. And alpha always means blood vessels or vascular smooth muscle. So now if we antagonize that alpha receptor response, then we will vasodilate, which in turn will lower the blood pressure. We will also relax the smooth muscle of the urinary system and therefore help the patient urinate easier. And so many times medications called are ending in Zocin, such as prozocin, doxazocin, but sometimes usually used for primary treatment of the prostate disorders or urinary tract outlet obstructions, but can also be used in the management of hypertension because they cause this vasodilation that will help us reduce the blood pressure. And then on the beta side, we have to distinguish between beta one and beta two receptors. And for that always think that beta one, we have one heart, beta two, we have two lungs. So they're usually beta one receptors are mostly in the heart and beta two are in the lungs. And so then we have beta blockers or beta adrenergic agonists. And so knowing that these receptors sit in the heart and the lungs, whether it's beta one or two, they can affect the heart rate as well or in turn than also the blood pressure. So now the beta blockers always end in LOL, such as in metoprolol, tenolol, those kind of medications. And then they come in a cardioselective versus non-cardioselective version. So that means that cardioselective beta blockers only affect beta one, cardioselective, we have one heart. Where beta or where non-selective beta blockers may affect beta one and beta two receptors. And therefore, if we do not wanna affect the beta two receptors in the patient's lungs, we have to consider that. And so conditions that might not be beneficial to administer a non-cardioselective beta blocker would be anything that has to do with the lungs. So, such as patients with underlying asthma or COPD, they're always better off getting cardioselective beta blockers because we know that medication is only gonna affect that beta one, their heart receptors and not their lungs. So keep that in mind, alpha is vascular smooth muscle, beta refers to heart, beta one, heart, beta two, lungs.