 Although God has sufficiently revealed himself in creation alone it is a testimony to the depravity of man that men suppress the truth of God in their unrighteousness. They refused to glorify him as God nor were they thankful. They exchanged the truth of God for the lie and they worshiped and served the creature rather than the Creator. In all of this God is vindicated in pouring out his wrath against the sinner. All men, Paul is speaking of here in a general way, all men universally are condemned by the law as sinners where all are found guilty before God. All their mouths are stopped. They have no defense. They are inexcusable.