 Hello everyone. The topic of the paper is Zola of DWI and DCMRI in predicting histopathologic grade of plasma cervix, a preliminary report under the guidance of Dr. Yatish Garwad, Dr. Kipika Sindhwani, Dr. Vijay Zutshi, Dr. Gidia Khanna of Vardman Mahavir Medical Collegium Hospital, New Delhi. Now, cervical cancer ranks as the second leading cause of female cancer in India. Revised ego staging is allowed the use of any imaging modality like CT and MRI and or pathological findings for evaluation of local and extra uterine cervical cancer spread for its accurate staging. It has been seen in early stages of cervical cancer, pathological parameters like tumor size, depth of invasion, lymphococcus, disinfusion are of prognostic value. Tumor grading will determine the course of disease and therapeutic outcome and survival. New MRI techniques like diffusion-related imaging and dynamic contrast MRI can assist the changes in tissue cellularity, perfusion and tissue physiology and can act as parameters and biomarkers of tumor biological behavior. ADC values seem to be the reason for medical malignancy which pollutes with increased cellularity. Thus, poorly-difficult tumors have lower ADC and help predict more prognosis. Studies have also shown that increased permeability areas with increased gay transcensuring enhancement were composed of cancer cell physicals and were more responsive to radiation therapy. Now, AIM and objectives were to determine the relationship of tumor ADC and gay trans-values with histopathological grading and staging of cervical cancer. Methodology. State time was a prospective cross-sectional observational institute review board approved in a tertiary test center, DMMC Subsectional Hospital. Sample size was 13, considering adult fever patients with clinical suspicion of Casinova subjects. It's an ongoing study. Inclusion criteria was adult females with clinical suspicion of cervical cancer. Exclusion criteria were patient with any MR contraindications in static pacemaker, allergy or contraindication to gallium contrast material. Patient have received any kind of treatment for the same illness. Coal cell was histopathology from core biopsy. Now, patient with clinical suspicion of CS subjects were clinically evaluated and informed concerns were taken. It was followed up by MRI conductors treated with standard sequences and with BWIN, tumor ADC and DCE pharmacokinetic parameters that state rounds were calculated, followed up by biopsy to assess the histopathological type and grading, which was ghostly, followed up by statistical analysis. Now, my observations patient was 57 years old female with bleeding TB. Exiled T2 and SASG2 shows a head presence lesion involving the cervical lesion. Followed up by WIDW shows a hybrid 10-signal followed up by hyper 10-signal ADC showing restriction. Now, ADC mean and ADC minimum calculated. ADC mean was calculated by drawing a manually drawn ROI encompassing the whole lesion, whereas ADC minimum was calculated by drawing ROI of at least 10 mm square area and then putting up manually over the lesion to find the minimum ADC value. ADC mean came out to me 92.2 in this patient and ADC minimum came out to me 899.2. Followed up by DCE, the ROI was kept in a lesion and the reference ROI was kept in myometrium as in some cases even the syriacal stroma was involved. Now, the curve showed that the syriacal lesion mass generated early enhancement as compared to the myometrium. 8-signal lesion came out to be 0.577. Histopathology showed that it was a well-difficient submersive CA cervix. Patient who was 60 or even with again history of bleeding TB and passage of clots, HZLT2 showed, SH2 showed a lesion involved in syriacal area. BWI showed that this lesion was districting. ADC minimum came out to be 773.2. ADC mean came out to be 887.6. On DCE, the lesion again showed early enhancement as compared to the myometrium. K-trans came out to be 858.4 and the histopathology showed that it was a moderate differentiated squamous cells CA cervix. Patient 3 was 31 year old female bleeding TB and passage of clots. HZLT2 showed a mass generated involving the syriacal lesion. The diffusion weighted showed that the lesion was districting. ADC minimum came out to be 539.7 and ADC mean came out to be 786.1. On dynamic contrast, the lesion showed early enhancement again as compared to the myometrium. 8-signal lesion came out to be 0.850 and on histopathology it was a poorly-difficient squamous cell CA cervix. Now, compiling the results, the demographic shows that out of 13 patients, 7 patients are moderate deficient squamous cell CA cervix, 3 were poorly differentiated and 3 were very differentiated. Going on to the fecal staging, 7 patients were stage 2B, 3 patients were stage 3, 1 patient were stage 4, 1 patient was stage 1B and 1 was stage 2B. In the compiling results, it has been seen the mean ADC minimum and K-trans value showed significant association with the grade. That is, poorly-differentiated deletions had minimum or less ADC as compared to well-differentiated, which are higher ADC. Similarly, median K-trans were higher for poorly-differentiated tumors and was lower for well-differentiated tumors. There was significant association as P-value was less than 0.05. Now, coming on to the correlation of stage with ADC-variant K-trans, there was no significant correlation of ADC-values with the K-trans as the K-values did not come out to be less than 0.05. The scatter plots showing that there was no significant correlation between ADC-values and staging or with K-trans and staging. Now, discussing previous studies with Liu et al showed that there was significantly positive linear correlation between tumor cellular density and grade of tumor. Both minimum ADC-value were correlated negatively with cellular density and with the original grade of tumor. Staring into the Yamashita showed that on a dynamic MR, area of the intense homogenous transplants showed increased permeability and increased K-value. These very large areas were predominantly composed of cancer cell vesicles and radiation therapy were more infected with inherited tumors with higher chocoballity. A certain study showed that there was significant difference between mean ADC value of tumor grade and other tumor grades. Mean ADC value was less than 0.05 as compared to ADC-value and mean ADC value were less in early stage as compared to the ADC value of the stage. Present study in the hospital showed that there was significant association of minimum ADC value and K-trans value with the histopathological grade of MSI and CSRVX. No significant correlation of ADC and K-trans value was seen with the stage of tumor. Now, moving on to conclusions, proofs that the minimum ADC value and K-trans value shows association with tumor histopathological grade. Therefore, DWR and DC MRI can provide an objective method for predicting histopathological grade and can be used as a biomarker for prognosticating cancer circuits. Now, these are my references that I have used.