 This study investigated the effects of an innovative eco-friendly process called Datant Instantenee Controli, DIC, combined with tripolium extraction, DC tripolium, on the extraction of hasperidin from orange peels. The DIC pretreatment increased the extractability of hasperidin from 1.55 to 4.67 fold compared to untreated DIC orange peels. Additionally, the radical scavenging activities of the extracts were either enhanced or preserved depending on the DIC tripolium conditions. The optimal DIC tripolium extraction conditions, which allowed for the maximum extraction of hasperidin, corresponded to a DIC-saturated steam pressure of 599.4 kilopascals and a DIC pretreatment time of 38 seconds. This article was authored by Mariam Ben-Abdulla, Morid Chadney, Numa Myrie, and others.