 The study highlights the importance of using single-photon emission-computed tomography, SPECT, for evaluating myocardial repair and regeneration therapies, as it offers high sensitivity, quantitative cell tracking in addition to assessing myocardial perfusion and function on both cross-sectional and longitudinal basis. This article was authored by LaCache Tequilli, Weicheck Schott, Ava Quichine, and others.