 The US National Institutes have health established the Clinical and Translational Science Award, CTSA, program in response to the challenges of translating biomedical and behavioral interventions from discovery to real-world use. We propose that the CTSA program takes advantage of the momentum of the field's capacity building in three ways, integrate state-of-the-science implementation methods and designs into its existing body of research. This article was authored by Sehun Hwang, Sarah A. Bacon, Cathy L. Melvin and others.