 BRG1 is essential for heart regeneration in zebrafish as well as in other species such as humans. It has been shown that BRG1 interacts with KDM7AA to control the expression of notch family genes which are involved in cell differentiation and proliferation. This interaction is important for proper heart regeneration following injury. This article was authored by Qing Li Xiao, Jun Jiahu, Fang Wang, and others.