This video is an introduction to the cre-lox system of conditional mouse genetic engineering and tools available in the Mouse Genome Informatics database, found at www.informatics.jax.org
Described are (1) conditional (floxed) alleles with recombinase recognition sites inserted to flank the gene of interest and (2) identification and characterization of recombinases used for tissue-specific genome remodeling.
Powerpoint slides can be downloaded for review alongside, as well as a Module 2 (cre) worksheet to assist with learning page navigation is provided on Google+.