 Metal organic frameworks, MOFs, have been investigated extensively for use in biomedical applications due to their unique properties such as high surface area, porosity, and tunable pore size. These features make them ideal candidates for drug delivery, as they can be used to encapsulate or adsorb drugs, proteins, and nucleic acids. Additionally, MOFs can be chemically modified to incorporate targeting moieties, enabling them to specifically target diseased cells. Furthermore, MOFs can also be used to deliver therapeutics directly into cells, which can lead to improved efficacy and reduced side effects. Despite these advances, there remain several challenges and opportunities for further research and development. This article was authored by Yu Jia-sun, Li Weijing, Yu Yong, and others.