 This paper provides an overview of modern literature on the incidents, mortality, evolution of reconstructive and plastic operations as well as the algorithm of their application in cancer of the organs of the head and neck. It also discusses the results of randomized studies on the surgical treatment of head and neck cancer as well as the challenges associated with rehabilitation and quality of life. Specifically, it focuses on the experiences of leading experts in the field of reconstructive surgeries for tumors of individual localizations as well as the impact of one-stage plastics on the quality of life of patients. Additionally, the paper compares the results of the application of the pectoralis major myocutaneous flap and the anterolateral thigh free flap, which revealed that the frequency of complications in the latter is significantly lower. Furthermore, the paper examines the effectiveness of palliative operations with simultaneous reconstruction using both free and pedacled flaps in patients with locally advanced head and neck cancer. This article was authored by Dr. Sanjanov, A. Mudenoff, R. Z. Yoldoshev, and others. We are article.tv, links in the description below.