 The study aims to quantify the impact of diabetes on tuberculosis outcomes through a systematic review and meta-analysis. The results show that patients with diabetes have an increased risk of failure and death during tuberculosis treatment, as well as an increased risk of relapse. The study also found that diabetes is associated with an increased risk of death during tuberculosis treatment, with the effect estimate increasing to 4.95 when adjusted for age and other potential confounding factors. The studies assessing sputum culture conversion after two to three months of tuberculosis therapy were heterogeneous, with relative risks that ranged from 0.79 to 3.25. Overall, the study highlights a need for increased attention to treatment of tuberculosis in people with diabetes, which may include testing for suspected diabetes, improved glucose control, and increased clinical and therapeutic monitoring.