 We found that SZR104 had a more pronounced effect than KYNA on the morphology of cultured microlia. Specifically, SZR104 caused hypertrophid microlia with larger cell bodies, increased perimeters, and higher convex hull values. Additionally, SZR104 decreased the roughness and density of the cells, while increasing the fractal dimension and maximum span across the convex hull. These results suggest that SZR104 may be more effective at reducing inflammation than KYNA. This article was authored by Melinda Sobo, Noemi Leko, Carolina Delca, and others.