 Primary sclerosing cholangitis, PSC, is a chronic inflammatory condition of the bald ducts, which can lead to cirrhosis and liver failure if left untreated. Research has shown that gut microbiota may play a role in the development of this disease, but the exact cause remains unknown. In this study, researchers found that certain types of bacteria were more common in people with PSC than those without it. They also discovered that these bacteria could be used to develop a treatment for PSC. The researchers created a lytic phage cocktail that specifically targets one type of bacteria, called klepsilinumoni, which was found to be present in higher numbers in people with PSC. When given to mice with PSC, the phage cocktail reduced the amount of the bacterium in the animals' bodies and improved their health. This suggests that the phage cocktail could potentially be used as a treatment for PSC. This article was authored by Misotica Ichikawa, Nobuhiro Nocomoto, Sharon Credo Rousseau, and others. We are article.tv, links in the description below.