 This study aimed to quantify the impact of fake news on vaccination decisions by analyzing the relationship between the popularity of searches, the proportion of fake news, and the number of vaccination doses administered in Taiwan. The results showed a significant positive-adjusted coefficient for vaccine availability and a negative-adjusted coefficient for the interaction term between fake news percentage and Google Trends level. The Johnson-Amen plot revealed that when a proportion of fake news exceeded 39.3 percent, the Google Trends level had a significant negative-adjustment effect on vaccination doses for the following week. This article was authored by Yan Pinchin, Iing Chen, Kaichou Yong, and others.