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Understanding the biological machinery by cryogenic TEM imaging and structure determination

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Published on Jan 29, 2018

Life is composed of four fundamental building blocks: lipids, sugars, nucleic acids, and amino acids. These basic building blocks polymerize and assemble into the living world around us. Historically, understanding how this organic chemistry creates the machinery of life required crystallization and x-ray diffraction methods, or were limited to sizes solvable by NMR spectroscopy. Today, advances in cryogenically preserving biological assemblies and imaging them by Transmission Electron Microscopy are revolutionizing our understanding of these molecular assemblies in near native conditions with spatial resolutions ranging from organismal to near atomic resolutions. This webinar discusses these advances and why the researchers behind them were recently award the Nobel Prize in Chemistry.

Presented by NCI Southwest and NACK Network.
Hosted by ATE Central.

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