 Trimethylamine anoxide, TMAO, is a compound produced by bacteria in the digestive system and has been linked to several health issues including heart disease, stroke, and diabetes. It can be found in higher concentrations in people who consume a lot of animal protein or fatty foods, and it can increase the risk of developing these diseases. The compound is thought to cause endothelial dysfunction, which is when the lining of blood vessels becomes damaged and unable to function properly. This leads to problems like high blood pressure, hardening of the arteries, and other cardiovascular issues. Studies suggest that TMAO may contribute to the development of these diseases by causing inflammation, increasing oxidative stress, activating platelets, and reducing vascular tone. Researchers are currently investigating ways to reduce TMAO levels in order to prevent or treat these diseases. This article was authored by Maya Maishenmugam, Sophie Bellange, and Chen Huailio. We are article.tv, links in the description below.