 This research has developed a new type of nanoparticle delivery system that combines chemotherapy and immunotherapy to treat cancer. The nanoparticles contain two types of adjuvant molecules, one to increase the amount of chemotherapy drug released into the tumour, and another to activate the patient's own immune system against the tumour. The nanoparticles also have a special structure that allows them to be easily targeted to the tumour site. When injected into the body, these nanoparticles are able to deliver higher doses of chemotherapy directly to the tumour while reducing side effects elsewhere in the body. In addition, they stimulate the patient's immune system to recognise and attack the tumour, resulting in more effective treatment. This article was authored by Bing Ma, Yin Ying Ma, Bo Deng and others.