 So, I was very much influenced by the Human Genome Project first because my laboratory, along with several other laboratories, were participants in it. We actually were involved in the first mapping and then sequencing of the human genome. It had a huge impact on me from doing that kind of participation, but also on my work. I had just started a few years earlier working on human genetics, trying to understand the genes that cause disease when they're mutated, in particular, Huntington disease and then later some other neurological diseases, and that has had an lasting impact. I still do that to this day. Prior to the genome project, I had worked on gene expression on a sort of biochemical reductionist level, and the genome project has greatly influenced the way that I do that still, but now on a global genome-wide level with the ENCODE project and many, many other approaches that we use to try to understand how genes play a role in disease, as well as basic biology and human health.