 Advances in nanoparticle, NP, production and demand for control over nanoscale systems have had significant impact on tissue engineering and regenerative medicine. NPs with low toxicity, contrasting agent properties, tailorable characteristics, targeted slash stimuli response delivery potential, and precise control over behavior have made it possible their use for improving engineered tissues and overcoming obstacles in term. This article was authored by Milad Fafia-Chakaluye, Helena Knopf-Marquez, Helena Knopf-Marquez, and others.