How Drugs and Booze affect your Brain





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Published on Mar 27, 2014

You know that drugs and alcohol affect you, but how do they actually make your body change?

In this video we talk a bit about how drugs and booze affect your brain, and if you join us next time we'll go even further into how these substances affect your mood and overall health.

If you're interested, here are some good places to learn more:

*The first neurotransmitter we reference is called GABA- it's responsible for regulating neuron excitation http://en.wikipedia.org/wiki/Gamma-Am...
*When we reference neurotransmitters that control memory and learning, we are talking about the NMDA system http://en.wikipedia.org/wiki/NMDA_rec...
*Two more good resources can be found below

So spread the word! (And be sure to subscribe for more Things You Should Know)

-Team TYSK

Features the song "Wickenden Kids" by the Rare Occasions - http://therareoccasions.bandcamp.com/

Citations (enable annotations to view):
Crews, Fulton T., and Kim Nixon. "Mechanisms of neurodegeneration and regeneration in alcoholism." Alcohol and Alcoholism 44.2 (2009): 115-127.

Di Marzo, Vincenzo, et al. "Endocannabinoids: endogenous cannabinoid receptor ligands with neuromodulatory action." Trends in neurosciences 21.12 (1998): 521-528.

Katona, István, et al. "Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons." The Journal of neuroscience 19.11 (1999): 4544-4558.

Lovinger, David M., Geoffry White, and Forrest F. Weight. "Ethanol inhibits NMDA-activated ion current in hippocampal neurons." Science 243.4899 (1989): 1721-1724.

McBride, Wl J., et al. "Serotonin, dopamine and GABA involvement in alcohol drinking of selectively bred rats." Alcohol 7.3 (1990): 199-205.

Meier, Madeline H., et al. "Persistent cannabis users show neuropsychological decline from childhood to midlife." Proceedings of the National Academy of Sciences 109.40 (2012): E2657-E2664.


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