 Aribatrisumetranus is a species of plant native to Sumatra, Java, and Borneo in Indonesia. Little research has been done on its activity, but this study aimed to explore the potential of its leaf and twig extracts as sources of an anti-diabetic agent through the alpha-glocosidase inhibition mechanism. The results indicated that the leaf extract had higher potential than the twig extract as an alpha-glocosidase inhibitor and antioxidant agent. Additionally, the study identified several compounds within the extracts that have a high affinity for alpha-glocosidase inhibition. These findings suggest that aribatrisumetranus could potentially be used as a source of natural alpha-glocosidase inhibitors. This article was authored by Dela Rosa, Berna Ilia, Muhammad HaNafi, and others.