 Coalesce is an online training tool designed to help researchers develop the skills needed to work effectively in interdisciplinary teams. It was created by the National Academies of Sciences and has been used by over 16,000 people since its launch in 2011. This study evaluated the effectiveness of the tool by comparing the performance of users from different disciplines before and after they completed for modules. The results showed that users from both biomedical and non-biomedical fields improved their knowledge, attitudes and skills after completing the modules. Additionally, those from the biomedical field had similar improvements regardless of whether or not they completed the SCITS Encyclopedia module. These findings suggest that Coalesce can be used to improve the ability of researchers to work in interdisciplinary teams. This article was authored by Bonnie Spring, Ekaterina A. Kleiko, Philip W. Rack and others.