Editing Our DNA with CRISPR: The Promise and Peril of Rewriting Life





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Premiered Apr 19, 2019

The breakthrough technology CRISPR now allows us to modify genes with ease and precision, and for the first time in history, human beings have the keys to our own evolution. In this program geneticists and bioethicists take you on a journey deep inside your DNA, as we discuss the promise and peril of interfering with the code therein.

PARTICIPANTS: Fred Gould, Josephine Johnston, Neville Sanjana, Sam Sternberg

MODERATOR: Lesley Stahl

MORE INFO ABOUT THE PROGRAM AND PARTICIPANTS: https://www.worldsciencefestival.com/...

This program is part of the “Big, the Small, and the Complex,” series sponsored by The Kavli Foundation and The Norwegian Academy of Science and Letters. The Kavli Prize recognizes scientists for their seminal advances in astrophysics, nanoscience, and neuroscience.

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0:04 - Opening film
2:14 - Panelist intros
3:54 - Medical applications for CRISPR
5:55 - CRISPR’s potential in plants and animals
7:00 - Bringing back extinct animals
8:24 - Negative aspects of using CRISPR
9:31 - Manipulating genes and evolution before CRISPR
14:23 - Tinkering and modifying as a part of human nature
15:51 - Tools of genetic engineering before CRISPR
18:03 - Inspiration from nature in bioengineering
19:13 - Have any GMO fears been realized?
21:42 - Intro to CRISPR film
23:41 - Explanation of CAS9
27:37 - What is so revolutionary about CRISPR?
34:08 - Benefits of CRISPR for treating non-heritable diseases
36:47 - How will we administer CRISPR-altered medicines to patients?
39:37 - CRISPR as open-source technology
42:23 - Regulating CRISPR use in humans


- Produced by Justin Weinstein
- Opening animation by Josh Kurz and Chris Metzler of Tilapia Film
- Music provided by APM
- Additional images and footage provided by: Getty Images, Shutterstock, Videoblocks

This program was recorded live at the 2018 World Science Festival and has been edited and condensed for YouTube.


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