 The study aimed to evaluate community clinical linkages, CCLs, for increasing human papillomavirus, HPV, vaccination rates in the U.S. through innovative partnerships between community and clinical entities. The research employed an iterative, case study approach with nine CCLs on HPV vaccination collected from representatives from the community organization and clinical setting. Thematic content analysis was used to analyze and interpret data, revealing five CCLs that included a federally qualified health center as the clinical partner, and five that included a nonprofit organization as the community partner. Five CCLs reflected clinically focused integration wherein engagement occurs in the community, but vaccine delivery and follow-up occur in the clinical setting. The study's results will guide HPV vaccination promotion, education, and intervention efforts, providing an opportunity to study the adoption, integration, and enhancement of evidence-based approaches to increase HPV vaccination.