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AHA: Center Stage Again Belongs to Antithrombotics

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Published on Nov 11, 2011

ORLANDO -- With new contenders in the field, the antithrombotic arena is likely to again steal the spotlight at the American Heart Association meeting.
And one of the showstoppers is sure to be the ATLAS ACS 2 study testing the oral Xa inhibitor rivaroxaban (Xarelto) for acute coronary syndrome, according to Christopher Cannon, MD, a cardiologist at Brigham and Women's Hospital in Boston and Editor-in-Chief of CardioSource.
Cannon previewed some of the trials via webcam in an exclusive interview with MedPage Today.
Topline results released from the ATLAS ACS 2 trial in September were positive enough that drugmaker Bayer said it intends to file for the new indication by the end of the year.
Further buzz arose from an unusual move by the AHA -- accepting the study as a last-minute add to the 21 other late-breaking clinical trial presentations already announced for the meeting.
Results of another antithrombotic study on that list, the TRACER trial with vorapaxar, have also been partially revealed, although they went in the opposite direction, Cannon noted.
Other notable studies in the late-breaker lineup include the CPORT E trial testing elective PCI at community centers, the battle of the statins in SATURN, and data on the novel HDL-raising drug evacetrapib from the same CETP-inhibitor class as anacetrapib that made waves at the meeting last year.

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