 The Learning Health System at LHS is a framework designed to improve patient care by generating and using high-quality evidence in everyday clinical settings. Despite its potential benefits, there have been significant barriers to its implementation, including tension between researchers, health care providers, and funding agencies. To overcome these barriers, this paper proposes eight strategies to help facilitate the adoption of the LHS. These include prioritizing timely, rigorous, and cost-effective research, aligning incentives among stakeholders, leveraging existing infrastructure, and creating a culture of collaboration. By taking these steps, we can ensure that the LHS becomes a reality and ultimately lead to improved patient care. This article was authored by Robert J. Reed and Sarah M. Green.