 This paper reports a rare case of secretory breast cancer, SBC, in an eight-year-old girl with no skin rupture or lymph node enlargement, who underwent two surgeries and had a good prognosis. The patient was diagnosed with SBC, which is highly prevalent among pediatric breast cancers and has a good prognosis due to the ETv6 NTRK3 fusion gene. SBC differs from basal triple negative breast cancer, TNBC, in clinical presentation, treatment, and prognosis, highlighting the importance of individualised treatment plans for SBC patients. This article was authored by Li Xiangxia, in Anjong, Jingcheng Wu, and others.