 The SIMSMOKE model was developed to estimate the impact of tobacco control policies on smoking and smokeless tobacco, SLT, prevalence and attributable deaths. This study applied the model to examine the impact of policies implemented between 1993 and 2018 on smoking and SLT prevalence in Kentucky. The model projects that these policies reduce smoking prevalence by 23.7% and SLT prevalence by 4.9%. These reductions are expected to continue through 2060, with smoking prevalence projected to decrease by 41% and SLT prevalence by 25%. Increased cigarette prices were found to be the most effective policy in reducing both smoking and SLT prevalence. This article was authored by Luz Maria Sanchez Romero, Eugene Yuan, Yamingly, and others.