 The Clinical Research Data Mart, CRDM, is a data repository developed at Duke University to facilitate access to electronic health record, EHR, data for researchers. It contains patient-level data elements needed for research studies, is accessible through a code-based query system, and provides a secure environment for storing and analyzing sensitive EHR data. The CRDM has been used to support several research projects, including those related to population health and clinical outcomes. This article was authored by Jillian H. Hurst, Yaxing Liu, Pamela J. Maxson, and others.