 Green synthesis of N-piece from various metal ions using plant extracts has been reported, but a clear understanding of the mechanism and bio-activities of these biogenic N-piece is lacking. The presence of plant-derived compounds in G-N-P-s might contribute to their better bio-activities than chemically synthesized N-piece. Further research on the mechanisms of green synthesis and high throughput screening of stabilizing slash capping agents on the physical chemical properties of G-N-P-s is necessary to fully realize the potential of green nanotechnology. This article was authored by Gregory Marslyn, Karthik Sairam, Kezar Makboul, and others.