 an electronic health record EHR algorithm was developed to identify healthy individuals for participation in clinical trials. The algorithm was tested by comparing three different methods of contacting potential participants, letters, phone calls and the EHR patient portal. The results showed that the EHR patient portal was the most effective method for identifying healthy individuals with a higher rate of success and lower effort and cost compared to other methods. Additionally, most healthy individuals prefer to be contacted electronically through the EHR patient portal. This study suggests that the use of EHR data can be an efficient and effective way to recruit healthy research volunteers. This article was authored by Mary H. Semuels, Robert Schiff, Peter Beninato, and others.