 Welcome, everybody, to our fourth annual TCGA Scientific Symposium. My name is Katie Hoadley, and I'm going to be your co-chair for today, and tomorrow we'll be leading. And we have a wonderful selection of talks to present over the next couple of days, and hope you will enjoy them. And first off, I just want to introduce Jean Clemson and Carolyn Hunter, who are going to give us our current state of TCGA.