 This review discusses recent advances in synthesizing graphene quantum dots, GQDs, for drug delivery applications, including various drug delivery release modes such as EPR-PH and ligand-PH delivery release mode, EPR photothermal delivery release mode, core-shell photothermal magnetic thermal delivery release mode, and the challenges and prospects of GQDs in drug delivery. This article was authored by Chan Hong-Jiao, Shuebin Song, YLU, and others.