 The results of this study suggest that the A11-66E variant of the A1R gene does not increase the risk of developing type 2 diabetes mellitus or diabetic nephropathy. However, it may be associated with higher levels of systolic blood pressure and serum creatinine in those who have uncontrolled hyperglycemia. This article was authored by Mahmud Reza Moradi, Zahra Rahimi, Sonia Amiri, and others.