 This systematic review will assess the effectiveness of mobile technology interventions in improving health and healthcare outcomes globally. Studies will be included if they involve the use of mobile computing and communication technologies to improve diagnosis, investigation, treatment, monitoring and management of diseases, as well as health promotion interventions, and those designed to improve patient adherence to treatments or disease management programs. Additionally, studies involving the use of mobile technology to improve healthcare processes such as appointment attendants, result notification, and vaccination reminders will also be considered. This article was authored by Patelvikram, Golly Leandro, Felix Lambert and others.