 This study presents a novel method for extracting eucalyptus cellulose and producing nanofibers doped with nanomaterials, such as AG, CU, and GO2. The goal is to enhance the properties of cellulosic fibre. The results show that the distribution of nanoparticles is excellent without aggregation or agglomeration, and the ultraviolet blocking property and photocatalytic activity of the samples are improved. Additionally, the anti-inflammatory and cytotoxicity of the samples were investigated and demonstrated low toxicity to fibroblast cells. This article was authored by Farzane Yamin, Feytman Adafian, and Salazo Hurri.