 Rotavirus gastroenteritis imposes a heavy burden on low- and middle-income countries, particularly in the eastern Mediterranean region, WHO-MRO, where vaccine coverage remains low despite rotavirus vaccination being introduced in 19 out of 22 EM countries. Younger children are at higher risk, highlighting the need for increased vaccination coverage and surveillance systems to reduce the burden of rotavirus gastroenteritis in WHO-MRO countries. This article was authored by Celine Boudreux, Serda Osterich, Pria Pereira, and others.