 My mom passed away in the mid 90s and my brother was in the early 2000s. At that point it was purely cytotoxic therapy and both of them had lung cancer, which you know in that time frame was terrible. 200,000 people diagnosed a year and very, very few survived a year and a half. And now due to innovations, it's gotten so much better with I think the anti-PD1s, the immunoculogy has changed it. So now 20-30% minimum of those patients have a long-term survival. They are in a long-term remission. EGFR inhibitors, precision meds, the same sort of thing. That standard of care has dramatically changed. Overall if you look in the United States, roughly 1.8 million people are diagnosed every year. And over the last 20 years there's been a steady 2% improvement survival every year. So now out of the 1.8 million people, yes 600,000 people die, which is tragic, but that means 1.2 million people are living. We're doing better.