 Recent cell tracking studies have shown that murine hypertrophic chondrocytes can survive beyond terminal differentiation and give rise to a progeny of osteoblasts participating in endocondral bone formation. The study shows that a progeny of col-10-cree reporter labeled osteoprogenitor cells and osteoblasts appears in the primary spongiosa and participates, depending on the developmental stage, substantially intrabecular, endosteal, and cortical bone formation. The study also identifies a novel, small YFP-plus-os-plus cell type with mitotic activity in the lower hypertrophic zone at the chondrocytes junction, which termed CDOP, chondrocyte-derived osteoprogenitor, cells. These findings add to current concepts of chondrocyte osteocyte lineages and give new insight into the complex cartilage bone transition process in the growth plate. This article was authored by Jung Park, Matias Gepport, Svitlana Golovchenko, and others. We are article.tv, links in the description below.