 This systematic review found that while there have been studies on the role of platelet-rich plasma, PRP, in bone grafts, teeth osteosynthesis, and wound healing, there is limited peer-reviewed evidence on its safety and efficacy in treating hair loss. The available evidence has shown low quality and controversial results about PRP's effectiveness in treating non-psychotritional alopecia, including androgenetic alopecia and alopecia areata. Further randomized controlled studies with larger sample sizes and standard protocols are needed to investigate the efficacy and safety of PRP in treating hair loss. This article was authored by Azin Ayatollafi, and Hoseini, Jaila Ghulami, and others.