 The study compared the effectiveness of surgery and medicinal treatments for patients with complicated forms of diabetic foot syndrome, DFS. The results showed that the two-stage operative tactic involving opening wounds and small surgeries on the foot, followed by plastic reconstruction of damaged tissues and formation of a stump at the third of the shin, reduced mortality to 1.9%. Additionally, metatarsal resection and egg's articulation of toes occurred in 92.5% of cases due to incorrect orthopedic correction of the impaired supporting function. Overall, the study concluded that the most effective treatment for patients with complicated forms of DFS involves timely and accurate selection of surgical or medical treatments. This article was authored by S. H. Usupova, M. K. H. Nabiev, and K. J. Sahinov.