 Hi, this is Dr. Pramod Krishnan. I'm a consultant neurologist at Manipal Hospital, Bangalore. I specialize in epilepsy. A seizure indicates that a part of the brain is not working properly. This could be due to many reasons. It could be due to infections of the brain, injuries to the brain, birth injuries to the brain, tumors, blood clots. And in some cases, despite repeated testing, we may not be able to identify the cause. In such cases, we just say the seizures are due to an unknown cause. In a small number of patients, seizures could actually be due to the genes, genetic causes, which are very, very less.