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Vaccine Safety Conference Session 18: Dr. Romain Gherardi

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Published on Nov 14, 2011

Nanosized particles injected into muscle slowly disseminate within phagocytes

Dr. Romain K. Gherardi is a French specialist of neuromuscular diseases. He graduated in clinical Neurology and Pathology, and has been a Professor since 1990. He is working at the Henri Mondor hospital, the second largest hospital of Assistance Publique- Hôpitaux de Paris, located in Créteil and depending of Paris-Est University. He heads the department of Histology that includes both Neuropathologic and Clinical activities in the setting of a Neuromuscular disease reference center. He also heads an experimental research team entitled 'Cellular interactions in the Neuromuscular system" (INSERM U955-E10) at the Institut Mondor de Recherche Biomédicale (IMRB).

From 1983 to 2010, Gherardi has published 290 articles indexed in PubMed, and monitored 14 PhD and 10 MSc students on the topic of biology, pathology and clinics of the nervous and muscular system. He previously studied several immuno-inflammatory and toxic neuromuscular disorders (almitrine neuropathy, zidovudine myopathy, statin myopathy, etc). He is currently working on innate immune reactions to myoinjury, biodistribution of nanoparticles, and pathophysiology of 'macrophagic myofasciitis" a neurologic disease linked to the long term persistence of Alum adjuvant in monocyte/macrophage lineage cells.
Gherardi is reviewer for Science, N Engl J Med, Lancet, Ann Neurol, Arthritis Rheum, Stem Cells, Stem Cell Dev, Neuromuscular Disord, Muscle Nerve, etc. On the topic of macrophagic myofasciitis, he was an invited speaker by the Centers for Disease Control, WHO Geneva, French government agencies, the French Parliament committee on Gulf War syndrome, and a variety of national and international scientific and medical societies.

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