SICK S2 • E10

Will We Ever Cure Breast Cancer?





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Published on Oct 11, 2019

Breast cancer is the second most common cancer diagnosed in women in the United States, right behind skin cancer. But how far have we come in understanding this disease?
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While breast cancer largely affects women, it can also occur in men. Fortunately, thanks to awareness, early detection, and research, survival rates have increased. But, there’s still a lot to learn, so Seeker sat down with Professor Donald McDonnell from the Duke School of Medicine to find out more.

So what exactly is breast cancer?

Breast cancer affects the cells in the tissue of the breast. It starts when these cells develop abnormally and begin to divide and accumulate rapidly, eventually forming a lump or mass. 

Under the breast cancer umbrella, there are three major types: estrogen receptor-positive breast cancer, HER2-positive breast cancer, and triple-negative breast cancers. They’re all different, they progress differently, and the treatments for them vary.

While knowing the breakdown of the most common types of breast cancer is a start, there are also factors that can put someone at a greater risk of contracting this disease.

Some risk factors include things such as obesity, estrogen exposure and genetics. In fact, one area that has seen substantial progress, is the understanding of something called familial breast cancer. That is breast cancer passed down from generation to generation. 

Understanding the three main types of breast cancer, their risk factors, and current treatment options are just the first step. Learn more about the daily discoveries and innovations that are helping write a new chapter for breast cancer on this episode of SICK.

#BreastCancer #Health #Medicine #Seeker #Science #SICK
Soy might reduce risk of Breast Cancer:

Inhibition of ERRα Prevents Mitochondrial Pyruvate Uptake Exposing NADPH-Generating Pathways as Targetable Vulnerabilities in Breast Cancer:

ESR1 mutations lead to constitutive activation of ERα and resistance to aromatase inhibitors:

Susan G. Komen Foundation:
SICK is a new series that looks at how diseases actually work inside our body. We'll be visiting medical centers and talking to top researchers and doctors to uncover the mysteries of viruses, bacteria, fungi and our own immune system. Come back every Tuesday for a new episode and let us know in the comments which diseases you think we should cover next.
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