 In 2022, it is estimated that there will be approximately 4.8 million and 2.4 million new cancer cases, and 3.2 million and 640,000 cancer deaths in China and the US, respectively. Lung cancer is the most common type of cancer in China while breast cancer is the most common type of cancer in the US. Lung cancer is also the leading cause of cancer death in both countries. In the US, age-standardized incidents and mortality rates for lung cancer and colorectal cancer have decreased significantly over time, while rates of liver, stomach, and esophageal cancer have decreased gradually in China. Colorectal cancer rates have increased in China, while rates of prostate cancer and other seven types of cancer have increased in women. Population aging and increases in adult population size are major contributors to the increase in cancer deaths in both countries. Additionally, progress in cancer prevention and care in the US, and measures to actively respond to population aging, could help China to reduce their cancer burden. This article was authored by Chiang Fashia, Xuesi Dong, He Li, and others. We are article.tv, links in the description below.