What is the best way to give a talk that engages and informs your audience? Dr. McConnell gives helpful advice on preparing and presenting an effective scientific talk. She reviews the basics of PowerPoint or Key Note and gives advice on choosing fonts, colors and slide styles. She also recommends ways to structure your talk so the audience stays awake and engaged. Her final recommendation is practice, practice, practice! Whether you are a graduate student presenting journal club or a tenured professor giving an invited lecture, this talk is sure to prove useful.