 The study aimed to investigate the efficacy of a dietary improvement program for the treatment of major depressive episodes. A randomized controlled trial was conducted with participants receiving either an adjunctive dietary intervention or a social support protocol. The primary endpoint was depression symptomatology assessed using the Montgomery Asperg depression rating scale at 12 weeks. The results showed that the dietary support group demonstrated significantly greater improvement in depression symptoms compared to the social support control group with a number needed to treat a 4.1 based on remission scores. The study suggests that dietary improvement may be an effective and accessible treatment strategy for major depressive episodes, which could extend to the management of common comorbidities. This article was authored by Felice and Jacka, Adrienne O'Neill, Rachele Opie and others.