 Plectranthus-esculentus tubers were modified through acetylation, oxidation, carboxymethylation, serigel formation, acetylation-serigel formation, and acetylation-oxidation. These modifications resulted in changes in starch cineresis, swelling power, and solubility. Structural properties were evaluated using Fourier transform infrared, FDIR, spectroscopy, and X-ray diffraction, XRD, which confirmed the presence of acetyl groups at 1700 cm, 1, and carboxymethyl groups at 1579 cm, 1. Acetylated derivatives were resistant to cineresis, while the acetylated serigelized derivatives were typically amorphous. Thermal transitions occurred due to gelatinization in dispersions of the native starch and the derivatives, acetylated, oxidized, and acetylated, oxidized. The acetylated derivatives have potential in terms of shelf life, stability, and diverse opportunities for multiple applications in pharmaceutical and food industries. This article was authored by Ursula Chiemkeemers, Ruthie Gupta, Nelson Agarbo-Cechpi, and others. We are article.tv, links in the description below.